PGT-M in Thailand: Cost, Top Specialists & Hospitals

PGT-M identifies IVF embryos free from a specific inherited condition. A custom genetic probe is developed for your family's mutation before the IVF cycle begins. Embryos are biopsied at blastocyst stage, and each is classified as affected, carrier, or unaffected. Only unaffected embryos are recommended for transfer, preventing the condition from being passed to your child.

Probe development requires DNA from both partners and ideally from affected or carrier family members. This preparatory step takes four to eight weeks and is a one-time investment — the same probe can be reused for future cycles. PGT-M can be combined with PGT-A on the same biopsy for simultaneous chromosomal screening.

PGT-M in Thailand costs between $3,000 and $5,400. This covers genetic counselling, custom probe development for your specific mutation, embryo biopsy, genetic analysis, results consultation, and a written report. The IVF cycle itself is priced separately. If PGT-A is added to the same biopsy, that is an additional fee.

The PGT-M fee has two components. Probe development (the workup) is a one-time cost that covers DNA collection, linkage mapping, and probe validation. Embryo testing covers the biopsy, laboratory analysis, and results interpretation. Genetic counselling is included at both stages. If the probe has been developed for a previous cycle, the workup cost is not repeated.

The complexity of the mutation affects probe development cost — some mutations are more straightforward to target than others. The number of embryos tested, whether PGT-A is combined, and whether family DNA samples are available all influence the total. A reused probe from a previous cycle eliminates the development cost entirely.

Pricing varies by the complexity and scope of the procedure. Typical ranges at our partner hospitals in Thailand:

• PGT-M with existing probe (common conditions): $3,000–$3,800 — laboratory already has a validated test for the specific gene mutation
• PGT-M requiring custom probe development: $3,800–$4,800 — a customised test is built for a rare or family-specific mutation
• PGT-M with concurrent PGT-A: $4,500–$5,400 — combines single-gene testing with full chromosomal screening

Exact pricing is confirmed after your consultation and treatment plan are finalised.

PGT-M in Thailand costs 50–70% less than equivalent testing in the US ($7,500–$13,500), Australia (A$6,600–A$12,000), and UK (£6,000–£10,500). The saving is particularly meaningful because PGT-M is often needed alongside a full IVF cycle — the combined cost in Thailand is still typically below the PGT-M cost alone at home.

No additional stay is needed. Probe development happens before you travel (DNA samples are shipped). Embryo biopsy occurs during your standard IVF cycle. Results arrive while you are home. You return for a frozen embryo transfer of five to seven days once an unaffected embryo is confirmed.

For a recessive condition where both partners are carriers, each embryo has a 25% chance of being affected. If all embryos test as affected or aneuploid, options include another IVF cycle to produce more embryos, donor gametes, or alternative pathways. Genetic counselling prepares you for all possible outcomes before testing begins.

Despite PGT-M's high accuracy (above 98%), confirmatory testing during pregnancy is recommended. Chorionic villus sampling (CVS) at 11–13 weeks or amniocentesis at 15–18 weeks can verify the PGT-M result. This is standard clinical practice worldwide and provides additional reassurance.

Yes. PGT-M is performed at licensed clinics in partnership with accredited genetics laboratories. The biopsy technique is identical to PGT-A, and the molecular analysis uses validated platforms. Thai clinics offering PGT-M comply with the Assisted Reproductive Technology Act and follow international best-practice guidelines.

Diagnostic accuracy exceeds 98% when direct mutation testing and linkage analysis are combined. The use of family DNA samples further improves reliability. Misdiagnosis is rare but not impossible, which is why confirmatory prenatal testing is recommended. No genetic test achieves 100% accuracy — understanding this is part of the counselling process.

PGT-M can test for virtually any single-gene disorder where the causative mutation is known. Common conditions include cystic fibrosis, sickle cell disease, thalassaemia, Huntington's disease, BRCA1/BRCA2 mutations, spinal muscular atrophy, fragile X syndrome, and Marfan syndrome. If you carry a known mutation, your genetic counsellor will confirm whether PGT-M is available for your specific condition.

Our partner clinics have established PGT-M programmes in partnership with accredited genetics laboratories. They handle probe development, embryo biopsy, and analysis as a coordinated service — not a fragmented process involving multiple unconnected providers. The clinical team, embryology team, and genetics lab work together to deliver results efficiently.

PGT-M requires genetic counsellors who can explain inheritance patterns, interpret complex results, and help you make informed decisions. Our partner clinics provide this counselling as a core part of the service. The counsellors are qualified in medical genetics and experienced with the specific emotional dimensions of genetic condition screening.

Confirm the clinic has performed PGT-M for your specific condition before. Ask about probe development timelines and whether family DNA samples can be collected locally and shipped. Check whether PGT-A can be combined on the same biopsy. Confirm genetic counselling is included. And ask about the clinic's turnaround time from biopsy to results.

Each tested embryo receives one of three classifications. Unaffected means the embryo does not carry the condition and is suitable for transfer. Carrier means the embryo carries one copy of the mutation but will not be affected — carriers can be transferred if no unaffected embryos are available, depending on the condition. Affected means the embryo has the condition and is not recommended for transfer.

When both tests are performed, you receive comprehensive information about each embryo's chromosomal status and genetic condition status. The ideal embryo for transfer is one that is both euploid (chromosomally normal) and unaffected by the genetic condition. This combined approach gives you the highest confidence in the embryo selected.

Begin the probe development process as early as possible. DNA samples from you, your partner, and relevant family members can be collected at local laboratories and shipped to the genetics lab in Thailand. Your coordinator will arrange collection kits and logistics. Starting the workup early ensures no delays to your IVF cycle timeline.

The PGT-M quote covers genetic counselling, probe development, embryo biopsy, genetic analysis, results consultation, and a comprehensive written report. The IVF cycle is priced separately. If PGT-A is added, that is an additional line item. Medication and embryo freezing are also quoted independently.

Probe development takes four to eight weeks (done remotely before you travel). Your IVF cycle in Thailand takes two to three weeks. Results take two to three weeks after biopsy (you can be home during this time). A frozen embryo transfer takes five to seven days (a return visit). Total elapsed time from start to transfer is approximately three to four months, though your active time in Thailand is limited to two trips.