PGT-A Surgery in Thailand (Preimplantation Genetic Testing for Aneuploidy)

PGT-A screens your embryos for chromosomal abnormalities before transfer — helping your specialist select the embryo most likely to implant and develop into a healthy pregnancy. It is one of the most impactful add-ons to an IVF cycle, particularly for women over 35 or those with a history of miscarriage. Thailand's leading clinics offer PGT-A using the same next-generation sequencing platforms found in top US and European laboratories.

Procedure 1–2 weeks (biopsy to results)

Hospital Stay None (lab procedure; biopsy is part of IVF cycle)

Recovery N/A (laboratory procedure)

Minimum Stay No additional stay required

What Is PGT-A?

PGT-A — preimplantation genetic testing for aneuploidy — screens IVF embryos for chromosomal abnormalities before transfer. A tiny biopsy taken at the blastocyst stage is analysed using next-generation sequencing to confirm the correct chromosome count. Selecting euploid embryos improves implantation rates and reduces miscarriage risk.

The trophectoderm biopsy removes a small number of cells from the outer layer of the blastocyst without harming the inner cell mass that forms the baby. NGS technology screens all 23 chromosome pairs simultaneously, with results typically available within one to two weeks, enabling informed embryo selection for transfer.

Common Concerns PGT-A Can Address

Recurrent miscarriage with no identified cause
Multiple failed IVF cycles despite good-quality embryos
Advanced maternal age (35 and over)
Previous pregnancy affected by a chromosomal abnormality
Wanting to maximise your chance of success from each embryo transfer

Are You a Good Candidate?

Currently undergoing an IVF or ICSI cycle with embryos reaching blastocyst stage
Willing to freeze all embryos and wait for results before transfer
Understand that PGT-A improves selection but does not guarantee pregnancy
Open to genetic counselling before and after testing

Techniques & Options

PGT-A involves two key steps: a precise embryo biopsy and sophisticated genetic analysis. Both are performed by highly trained specialists using advanced technology. Your clinic will explain the process in detail and provide genetic counselling to help you understand your results.

The two main components of PGT-A are:

Trophectoderm Biopsy

A small number of cells (typically 5–10) are carefully removed from the trophectoderm — the outer layer of the blastocyst that will become the placenta. This layer is biopsied rather than the inner cell mass (which becomes the baby), ensuring the embryo itself is not harmed. The biopsy is performed by an experienced embryologist using a precision laser and micromanipulation tools.

Does not damage the inner cell mass that forms the baby
Performed at the blastocyst stage (day 5–6) for maximum accuracy
Embryos are vitrified immediately after biopsy

Next-Generation Sequencing (NGS) Analysis

The biopsied cells are analysed using next-generation sequencing technology, which reads the DNA to determine the chromosome count across all 23 pairs. NGS is the current gold-standard method for PGT-A, offering high accuracy and the ability to detect mosaicism (embryos with a mix of normal and abnormal cells).

Screens all 23 chromosome pairs simultaneously
Detects mosaicism and segmental abnormalities
Results typically available within 1–2 weeks

Recovery Timeline

Embryo Biopsy (Day 5–6)

When your embryos reach the blastocyst stage, the embryologist performs the trophectoderm biopsy. This is a laboratory procedure — you are not involved and there is nothing to recover from. Each embryo is vitrified immediately after biopsy to preserve its quality while the genetic analysis is completed.

Genetic Analysis (1–2 Weeks)

The biopsied cells are sent to a genetics laboratory — either on-site or to a partner facility — for next-generation sequencing analysis. Each embryo receives a result: euploid (normal), aneuploid (abnormal), or mosaic (mixed). You can return home during this waiting period.

Results Consultation

Your fertility specialist and genetic counsellor review the results with you. They explain which embryos are suitable for transfer, what the findings mean for your chances of success, and any implications of mosaic results. A clear written report is provided.

Frozen Embryo Transfer

A euploid embryo is thawed and transferred to your prepared uterus in a subsequent frozen embryo transfer (FET) cycle. This is a short visit of 5–7 days. Transferring a PGT-A-screened euploid embryo gives you the highest chance of implantation and a healthy pregnancy.

What to Expect

60–70% Implantation rate per euploid embryo transfer

Reduced Miscarriage Significantly lower miscarriage rates with screened embryos

All 23 Pairs Every chromosome screened with NGS technology

Safety & Risks

PGT-A is a safe and widely used procedure. The embryo biopsy is performed by highly trained embryologists, and the risk of damage to the embryo is very low. However, like all diagnostic tests, PGT-A has limitations that are important to understand.

Small risk of embryo damage during biopsy (under 1% at experienced centres)
False positive or false negative results (rare but possible)
Mosaicism may produce inconclusive or complex results

Not all embryos will reach blastocyst stage and be available for biopsy
PGT-A does not test for single-gene disorders (PGT-M is needed for that)
No guarantee of pregnancy even with a euploid embryo

Your specialist will explain that PGT-A is a screening tool, not a diagnostic guarantee. A small percentage of results may be inconclusive. Genetic counselling is provided before and after testing to ensure you fully understand the benefits, limitations, and implications of your results. Leading Thai clinics use experienced embryologists with high biopsy proficiency to minimise any risk to your embryos.

How Much Does PGT-A Cost in Thailand?

Our pricing is transparent and covers the full PGT-A process from genetic counselling to results — no hidden fees.

PGT-A

PGT-A testing package

From $2,000

Genetic counselling consultation
Embryo biopsy procedure
Chromosomal analysis (up to 8 embryos)

Results consultation
Report & recommendations
Dedicated care coordinator

Add Accommodation Package

Hotel, breakfast, airport transfers & 24/7 support

From $89 / night

Affordable suites on Sukhumvit Soi 23, a short ride from leading fertility clinics. Rooms include a kitchenette, daily breakfast, and access to the pool and fitness centre — a comfortable, budget-friendly base during your treatment.

A well-appointed serviced residence in the heart of Sukhumvit with full kitchen, washer-dryer, pool and gym. Ideal for patients on longer treatment cycles who want a home-away-from-home feel with hotel-level service.

A luxury hotel close to the clinic district, known for impeccable Japanese-standard service. Spacious rooms, an acclaimed spa, and 24-hour room service — the premium choice for a stress-free stay during treatment.

Common Questions About PGT-A

Everything you need to know before your procedure

PGT-A is a laboratory procedure performed on embryos during your IVF cycle, so no additional stay is needed beyond your IVF treatment. Results are typically available within 1–2 weeks. You may return for a frozen embryo transfer visit of 5–7 days once results are confirmed.

PGT-A screens embryos for aneuploidy — having too many or too few chromosomes. The most common aneuploidies include trisomy 21 (Down syndrome), trisomy 18 (Edwards syndrome), and trisomy 13 (Patau syndrome), as well as monosomies and other chromosomal imbalances that typically cause implantation failure or early miscarriage. PGT-A checks all 23 chromosome pairs.

Yes. Studies consistently show that transferring a PGT-A-screened euploid embryo improves implantation rates (60–70% vs 40–50% without testing) and significantly reduces miscarriage rates. The benefit is greatest for women over 35 and those with recurrent pregnancy loss. However, PGT-A may reduce the number of embryos available for transfer if several are found to be aneuploid.

The biopsy removes cells from the trophectoderm — the outer layer that forms the placenta — not from the inner cell mass that becomes the baby. At experienced centres, the risk of embryo damage is under 1%. Studies have not shown any increased risk of birth defects or developmental problems in children born from biopsied embryos.

Results are typically available within 1–2 weeks after the biopsy. During this time, your embryos are safely vitrified. You can return home and receive results remotely. Your specialist will arrange a consultation — in person or via video — to review the findings and plan the transfer.

This is a possibility, particularly for women over 40 where aneuploidy rates are higher. If all embryos are aneuploid, your specialist will discuss options including another IVF cycle, using donor eggs, or exploring other treatment paths. Knowing the result upfront avoids transferring embryos with very low implantation potential, saving time, cost, and emotional energy.

A mosaic embryo contains a mixture of chromosomally normal and abnormal cells. Mosaicism is detected in roughly 10–20% of biopsied embryos. Low-level mosaic embryos may still be considered for transfer in some circumstances, as a proportion can self-correct during development. Your genetic counsellor will explain the specific findings and help you make an informed decision.

Our quoted price covers genetic counselling, the embryo biopsy procedure, next-generation sequencing analysis for up to 8 embryos, results consultation, and a written report with recommendations. If you have more than 8 embryos, additional per-embryo fees apply. Your coordinator will provide a full breakdown before testing begins.

PGT-A analyses the sex chromosomes (X and Y) as part of the full chromosomal screen, so the sex of each embryo is identified. Whether this information is disclosed to you depends on local regulations and clinic policy. In Thailand, sex selection for non-medical reasons is not permitted under the Assisted Reproductive Technology Act.

PGT-A is most beneficial for women over 35, where aneuploidy rates increase significantly. For younger patients, the majority of embryos are likely to be euploid, so the added value of testing is smaller. However, PGT-A may still be recommended if you have a history of miscarriage, repeated IVF failure, or want to maximise your chance of success from a single transfer.

No. PGT-A screens for chromosomal abnormalities (wrong number of chromosomes), while PGT-M tests for specific single-gene disorders such as cystic fibrosis, sickle cell disease, or thalassaemia. PGT-M requires custom probe development for each condition and is used when one or both partners are known carriers of a genetic disorder. Both tests can be performed on the same embryo biopsy.

Dr. Natthida Chaisiri

MEDICALLY REVIEWED

Dr. Natthida Chaisiri

MEDICALLY REVIEWED

Fertility Specialist · Bangkok

Last reviewed: February 18, 2026

Medical References

What's Included

Genetic counselling consultation
Embryo biopsy procedure
Chromosomal analysis (up to 8 embryos)
Results consultation
Report & recommendations
Dedicated care coordinator

Ready to Get Started?

Speak with our care coordinators for a free, no-obligation consultation and personalised quote.

Speak to Our Team

PGT-A in Thailand